When change doesn't work, there's always hope. I hope and pray for the best but sometimes some random person or some random group of people just seem hell bent on throwing a wrench into the works. Rule of thumb: "Never underestimate the power of stupid people in large numbers."
In the macro we always risk the chance of unintended consequences....... On a personal level, in order to do the right thing we may possibly hurt some one, which may make it tougher to do what we believe to be right. Also in the micro we are more accountable, so it may be even more difficult. I suppose this is why our choices need to be balanced between our knowledge and our heart, this would be wisdom............