Last weekend I had this problem I've encountered many times before. It happens to all of us on occasion. Suffice to say, it took place in our bathroom. I was in the bathroom squeezing and squeezing so hard I was turning blue in my face and yet could not get anything out. You know how exasperating and frustrating that could be. No matter how hard I tried, the result was nothing.
My wife knocked on the bathroom door and yelled that I'd been in there over a half hour. "Is there a problem? Are you alright?", she asked. I told her I'd been squeezing and squeezing and couldn't get even a drop out. She told me to try using a bottle of citrate of magnesia or some milk of magnesia in the cabinet under the sink. I found this big bottle of milk of magnesia and pressed it really hard on the bottom of the tube of Colgate toothpaste. EUREKA !! It flowed right out of the tube.